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Gene Expression Data
Assay Details
Assay
Reference: J:248980 Guo H, et al., Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. Dev Biol. 2017 Oct 1;430(1):214-223
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7258075
Gene symbol: Scgb1a1
Gene name: secretoglobin, family 1A, member 1
Antibody: anti-CCSP
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2A Bronchiolar WT Scgb1a1: embryonic day 18.5 (more )
Note: Triple labeled: red - Scgb1a1; green - acetylated tubulin; blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS26: bronchiole club cell Present 2A Bronchiolar WT +DAPI , 2A Bronchiolar WT Scgb1a1 Expression in Club cells lining bronchilar airways.
Specimen 2A Bronchiolar TNRC6c-/- Scgb1a1: embryonic day 18.5; Tnrc6cGt(IST11346C2)Tigm/Tnrc6cGt(IST11346C2)Tigm (more )
Note: Triple labeled: red - Scgb1a1; green - acetylated tubulin; blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS26: bronchiole club cell Present 2A Bronchiolar TNRC6c-/- +DAPI , 2A Bronchiolar TNRC6c-/- Scgb1a1 Expression present and properly localized within mutant lungs, in a similar to that of wild type.
Specimen 2B Bronchiolar WT Scgb1a1: postnatal day 0 (more )
Note: Triple labeled: red - Scgb1a1; green - acetylated tubulin; blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS27: bronchiole club cell Present 2B Bronchiolar WT Scgb1a1 , 2B Bronchiolar WT +DAPI Expression in Club cells lining bronchilar airways.
Specimen 2B Bronchiolar TNRC6c-/- Scgb1a1: postnatal day 0; Tnrc6cGt(IST11346C2)Tigm/Tnrc6cGt(IST11346C2)Tigm (more )
Note: Triple labeled: red - Scgb1a1; green - acetylated tubulin; blue - DAPI.
Structure Level Pattern Image Note
TS27: bronchiole Weak 2B Bronchiolar TNRC6c-/- +DAPI , 2B Bronchiolar TNRC6c-/- Scgb1a1 Slightly reduced levels of expression at PN0 compared with wild type and E18.5 mutant lungs.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory