About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:248980 Guo H, et al., Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. Dev Biol. 2017 Oct 1;430(1):214-223
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7258075
Gene symbol: Scgb1a1
Gene name: secretoglobin, family 1A, member 1
Antibody: anti-CCSP
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2A Bronchiolar WT Scgb1a1: embryonic day 18.5 (more )
Note: Triple labeled: red - Scgb1a1; green - acetylated tubulin; blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS26: bronchiole club cell Present 2A Bronchiolar WT +DAPI , 2A Bronchiolar WT Scgb1a1 Expression in Club cells lining bronchilar airways.
Specimen 2A Bronchiolar TNRC6c-/- Scgb1a1: embryonic day 18.5; Tnrc6cGt(IST11346C2)Tigm/Tnrc6cGt(IST11346C2)Tigm (more )
Note: Triple labeled: red - Scgb1a1; green - acetylated tubulin; blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS26: bronchiole club cell Present 2A Bronchiolar TNRC6c-/- +DAPI , 2A Bronchiolar TNRC6c-/- Scgb1a1 Expression present and properly localized within mutant lungs, in a similar to that of wild type.
Specimen 2B Bronchiolar WT Scgb1a1: postnatal day 0 (more )
Note: Triple labeled: red - Scgb1a1; green - acetylated tubulin; blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS27: bronchiole club cell Present 2B Bronchiolar WT Scgb1a1 , 2B Bronchiolar WT +DAPI Expression in Club cells lining bronchilar airways.
Specimen 2B Bronchiolar TNRC6c-/- Scgb1a1: postnatal day 0; Tnrc6cGt(IST11346C2)Tigm/Tnrc6cGt(IST11346C2)Tigm (more )
Note: Triple labeled: red - Scgb1a1; green - acetylated tubulin; blue - DAPI.
Structure Level Pattern Image Note
TS27: bronchiole Weak 2B Bronchiolar TNRC6c-/- +DAPI , 2B Bronchiolar TNRC6c-/- Scgb1a1 Slightly reduced levels of expression at PN0 compared with wild type and E18.5 mutant lungs.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory