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Gene Expression Data
Assay Details
Assay
Reference: J:182768 Wong YL, et al., Smad1/Smad5 signaling in limb ectoderm functions redundantly and is required for interdigital programmed cell death. Dev Biol. 2012 Mar 1;363(1):247-57
Assay type: RNA in situ
MGI Accession ID: MGI:7257796
Gene symbol: En1
Gene name: engrailed 1
Results
Specimen 4E: embryonic day 11.5; En1tm2(cre)Wrst/En1+, Smad1tm1Abr/Smad1+, Smad5tm1Huy/Smad5tm1Huy (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 4E Expression in ventral ectoderm.
TS19: handplate ectoderm Present Regionally restricted 4E
Specimen 4F: embryonic day 11.5; En1tm2(cre)Wrst/En1+, Smad1tm1Abr/Smad1tm1Abr, Smad5tm1Huy/Smad5tm1Huy (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 4F Expression along dorsal-ventral axis comparable with control.
TS19: handplate ectoderm Present Regionally restricted 4F Expression along dorsal-ventral axis comparable with control.
Specimen 7A: embryonic day 11.5; En1tm2(cre)Wrst/En1+, Smad1tm1Abr/Smad1+, Smad5tm1Huy/Smad5tm1Huy (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 7A
TS19: handplate ectoderm Present Regionally restricted 7A Expression in ventral ectoderm.
Specimen 7B: embryonic day 11.5; En1tm2(cre)Wrst/En1+, Smad1tm1Abr/Smad1tm1Abr, Smad5tm1Huy/Smad5tm1Huy (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 7B Expression comparable with control.
TS19: handplate ectoderm Present Regionally restricted 7B Expression comparable with control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory