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Gene Expression Data
Assay Details
Assay
Reference: J:182768 Wong YL, et al., Smad1/Smad5 signaling in limb ectoderm functions redundantly and is required for interdigital programmed cell death. Dev Biol. 2012 Mar 1;363(1):247-57
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7257793
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen 3C: embryonic day 13.5; En1tm2(cre)Wrst/En1+, Smad1tm1Abr/Smad1+, Smad5tm1Huy/Smad5tm1Huy (more )
Note: Conditional mutant. Double labeled: green - Casp3; red - Hoeschst.
Structure Level Pattern Image Note
TS21: forelimb interdigital region mesenchyme Present 3C
Specimen 3D: embryonic day 13.5; En1tm2(cre)Wrst/En1+, Smad1tm1Abr/Smad1tm1Abr, Smad5tm1Huy/Smad5tm1Huy (more )
Note: Conditional mutant. Double labeled: green - Casp3; red - Hoeschst.
Structure Level Pattern Image Note
TS21: forelimb interdigital region mesenchyme Trace 3D Drastic decrease in number of expressing cells compared with control.
Specimen 3H: embryonic day 13.5; En1tm2(cre)Wrst/En1+, Smad1tm1Abr/Smad1+, Smad5tm1Huy/Smad5tm1Huy (more )
Note: Conditional mutant. Triple labeled: green - Casp3; red - Brdu; blue - Hoechst.
Structure Level Pattern Image Note
TS21: forelimb interdigital region mesenchyme Present 3H
Specimen 3I: embryonic day 13.5; En1tm2(cre)Wrst/En1+, Smad1tm1Abr/Smad1tm1Abr, Smad5tm1Huy/Smad5tm1Huy (more )
Note: Conditional mutant. Triple labeled: green - Casp3; red - Brdu; blue - Hoechst.
Structure Level Pattern Image Note
TS21: forelimb interdigital region mesenchyme Trace 3I
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
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