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Gene Expression Data
Assay Details
Assay
Reference: J:180785 Loebel DA, et al., Regionalized Twist1 activity in the forelimb bud drives the morphogenesis of the proximal and preaxial skeleton. Dev Biol. 2012 Feb 15;362(2):132-40
Assay type: RNA in situ
MGI Accession ID: MGI:7256618
Gene symbol: Hand2
Gene name: heart and neural crest derivatives expressed 2
Probe: Hand2 probe14
Probe preparation: labelled with digoxigenin RNA
Results
Specimen S5J: embryonic day 10.5; Twist1tm2Bhr/Twist1+ (more )
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Regionally restricted S5J Expression in posterior mesenchyme.
Specimen S5K: embryonic day 10.5; Twist1tm2Bhr/Twist1tm2.1Bhr (more )
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Regionally restricted S5K Expression not appreciably different from wild-type.
Specimen S5L: embryonic day 10.5; Mesp1tm2(cre)Ysa/Mesp1+, Twist1tm2Bhr/Twist1tm2.1Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Regionally restricted S5L Expression not appreciably different from wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory