About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:180785 Loebel DA, et al., Regionalized Twist1 activity in the forelimb bud drives the morphogenesis of the proximal and preaxial skeleton. Dev Biol. 2012 Feb 15;362(2):132-40
Assay type: RNA in situ
MGI Accession ID: MGI:7256607
Gene symbol: Gli3
Gene name: GLI-Kruppel family member GLI3
Probe: Gli3 probe27
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 5A: embryonic day 10.5; Twist1tm2Bhr/Twist1+ (more )
Structure Level Pattern Image Note
TS17: limb mesenchyme Strong Regionally restricted 5A Robust expression in anterior-poster gradient, becoming weaker posteriorly.
Specimen 5B: embryonic day 10.5; Twist1tm2Bhr/Twist1tm2.1Bhr (more )
Structure Level Pattern Image Note
TS17: limb mesenchyme Strong Regionally restricted 5B Expression not changed compared with wild-type.
Specimen 5C: embryonic day 10.5; Mesp1tm2(cre)Ysa/Mesp1+, Twist1tm2Bhr/Twist1tm2.1Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Regionally restricted 5C Expression reduced in anterior region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory