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Gene Expression Data
Assay Details
Assay
Reference: J:199480 Cao T, et al., Mouse limbs expressing only the Gli3 repressor resemble those of Sonic hedgehog mutants. Dev Biol. 2013 Jul 15;379(2):221-8
Assay type: RNA in situ
MGI Accession ID: MGI:7256301
Gene symbol: Hand2
Gene name: heart and neural crest derivatives expressed 2
Probe: Hand2 probe12
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4E1: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 4E1

Specimen 4E2: embryonic day 10.5; Gli3tm3.1Blnw/Gli3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud Weak Regionally restricted 4E2 Expression domain smaller compared to wild type.

Specimen 4E3: embryonic day 10.5; Gli3tm3.1Blnw/Gli3tm3.1Blnw, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud Absent 4E3

Specimen 4E4: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: forelimb bud Absent 4E4


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory