About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:273624 Bourgeois JR, et al., Loss of the neurodevelopmental Joubert syndrome causing protein, Ahi1, causes motor and muscle development delays independent of central nervous system involvement. Dev Biol. 2019 Apr 1;448(1):36-47
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7255024
Gene symbol: Myh2
Gene name: myosin, heavy polypeptide 2, skeletal muscle, adult
Results
Specimen 7A: postnatal day 21 (more )
Note: Triple labeled: green - Myh2; red - Myh7 (assay MGI:7255023); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS28: soleus type II muscle cell Present 7A
Specimen 7B: postnatal day 21 (more )
Note: Triple labeled: green - Myh2; red - Myh7 (assay MGI:7255023); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS28: vastus intermedius type II muscle cell Present 7B
Specimen 7C: postnatal day 21; Ahi1tm1Rujf/Ahi1tm1Rujf (more )
Note: Triple labeled: green - Myh2; red - Myh7 (assay MGI:7255023); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS28: soleus type II muscle cell Present 7C Reduced cross sectional area (CSA) of Type II muscle fibers compared to +/+ mice.
Specimen 7D: postnatal day 21; Ahi1tm1Rujf/Ahi1tm1Rujf (more )
Note: Triple labeled: green - Myh2; red - Myh7 (assay MGI:7255023); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS28: vastus intermedius type II muscle cell Present 7D Reduced cross sectional area (CSA) of Type II muscle fibers compared to +/+ mice.
Specimen 8A: postnatal day 21 (more )
Note: Triple labeled: green - Myh2; red - Myh7 (assay MGI:7255023); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS28: soleus type II muscle cell Present 8A
Specimen 8B: postnatal day 21 (more )
Note: Triple labeled: green - Myh2; red - Myh7 (assay MGI:7255023); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS28: vastus intermedius type II muscle cell Present 8B
Specimen 8C: postnatal day 21; Ahi1tm1Rujf/Ahi1tm1Rujf (more )
Note: Triple labeled: green - Myh2; red - Myh7 (assay MGI:7255023); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS28: soleus type II muscle cell Present 8C Significant reduction of cross sectional area (CSA) of Type II muscle fibers compared to +/+ mice, to a lesser extent than seen at 3 weeks.
Specimen 8D: postnatal day 21; Ahi1tm1Rujf/Ahi1tm1Rujf (more )
Note: Triple labeled: green - Myh2; red - Myh7 (assay MGI:7255023); blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS28: vastus intermedius type II muscle cell Present 8D No reduction in cross sectional area (CSA) of Type II muscle fibers compared to +/+ mice.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory