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Gene Expression Data
Assay Details
Assay
Reference: J:321248 Kinoshita N, et al., Force-dependent remodeling of cytoplasmic ZO-1 condensates contributes to cell-cell adhesion through enhancing tight junctions. iScience. 2022 Feb 18;25(2):103846
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7254910
Gene symbol: Tjp1
Gene name: tight junction protein 1
Antibody: Anti-ZO-1 (clone ZO1-1A12; 33-9100)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1B E3.5: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: blastocyst Present Punctate 1B ZO-1 E3.5 Expression in cytoplasmic puncta.
Specimen 1B1 (E3.5 mural): embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: blastocyst Present Punctate 1B1 (E3.5 mural) Significantly higher number of puncta in cytoplasm compared with E4.5 embryos.
Specimen 1B E4.5: embryonic day 4.5 (more )
Structure Level Pattern Image Note
TS5: blastocyst Present Regionally restricted 1B ZO-1 E4.5
Specimen 1B2 (E4.5 mural): embryonic day 4.5 (more )
Structure Level Pattern Image Note
TS5: blastocyst Weak Punctate 1B2 (E4.5 mural) Reduced number of cytoplasmic puncta compared to E3.5 embryos.
Specimen 1B3 (E4.5 polar): embryonic day 4.5 (more )
Structure Level Pattern Image Note
TS5: blastocyst Strong Regionally restricted 1B3 (E4.5 polar) Higher expression at plasma membrane compared to E3.5 embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory