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Gene Expression Data
Assay Details
Assay
Reference: J:321069 Lopez-Marquez A, et al., Sox9 is involved in the thyroid differentiation program and is regulated by crosstalk between TSH, TGFbeta and thyroid transcription factors. Sci Rep. 2022 Feb 9;12(1):2144
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6890427
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Antibody: anti-Nkx2.1 (PA0100)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. TTF-1 antibody MGI:6890423 may have been used in this assay.
Results
Specimen 1A E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: thyroid primordium endoderm Present 1A E9.5 Nkx2.1 , 1A E9.5 (merge) Expression in thyroid precursors emerging from pharyngeal endoderm.

Specimen 1A E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: thyroid primordium endoderm Present 1A E10.5 Nkx2.1 , 1A E10.5 (merge) Expression in thyroid precursors emerging from pharyngeal endoderm.

Specimen 1A E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: thyroid gland Present 1A E11.5 (merge) , 1A E11.5 Nkx2.1 Expression in thyroid precursors emerging from pharyngeal endoderm.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory