About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:320853 Mitomo K, et al., Hypoplasia of medial pterygoid process in sphenoid bone relates to decreased mesenchymal cell proliferation in the Runx2-haploinsufficient cleidocranial dysplasia mouse model. Arch Oral Biol. 2022 Mar;135:105358
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6888383
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Antibody: anti-Runx2 (sc-390351)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1E: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: chondrocranium cartilage condensation Present Regionally restricted 1E Expression in cells densely distributed in center of mesenchymal cell condensation of medial pterygoid process of sphenoid bone.
TS22: sphenoid bone chondrocyte Present Regionally restricted 1E Expression in some chondrocytes at lateral end of sphenoid bone.

Specimen 1F: embryonic day 14.5; Runx2tm1Kish/Runx2+ (more )
Structure Cell Type Level Pattern Image Note
TS22: chondrocranium cartilage condensation Present Regionally restricted 1F Expression in sparsely distributed mesenchymal cells beneath lateral end of sphenoid bone.
TS22: sphenoid bone chondrocyte Present Regionally restricted 1F Expression in some chondrocytes at lateral end of sphenoid bone.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory