Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tshz1tm1(flpo)Zjh
Name:	teashirt zinc finger family member 1; targeted mutation 1, Z Josh Huang
MGI ID:	MGI:6888001
Synonyms:	Tshz1-2A-FlpO
Gene:	Tshz1  Location: Chr18:84029752-84105831 bp, - strand  Genetic Position: Chr18, 57.53 cM
Alliance:	Tshz1tm1(flpo)Zjh page

Germline Transmission:	Earliest citation of germline transmission: J:296899
Parent Cell Line:	v6.5 (ES Cell)
Strain of Origin:	(C57BL/6 x 129S4/SvJae)F1

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Tshz1tm1(flpo)Zjh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Tshz1 (MGI:1346031)   Mutation details: The allele was generated by inserting a 2A-flpo expression cassette immediately after the STOP codon of the Tshz1 gene by homologous recombination in ES cells. (J:296899)

Activity:	Tissue activity of this recombinase allele
Driver:	Tshz1 (mouse) Summary of all recombinase alleles driven by Tshz1. Comparative matrix view of recombinase activities Alliance mouse Tshz1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tshz1 Mutation:	51 strains or lines available

Original:	J:296899 Xiao X, et al., A Genetically Defined Compartmentalized Striatal Direct Pathway for Negative Reinforcement. Cell. 2020 Oct 1;183(1):211-227.e20
All:	1 reference(s)