Lrrc10 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:319011 Brody MJ, et al., Lrrc10 is a novel cardiac-specific target gene of Nkx2-5 and GATA4. J Mol Cell Cardiol. 2013 Sep;62:237-46
Assay type:	RNA in situ
MGI Accession ID:	MGI:6887886
Gene symbol:	Lrrc10
Gene name:	leucine rich repeat containing 10

Probe:	Lrrc10 cDNA1
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

Specimen 2D: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: heart	Present		2D

Specimen 2E: embryonic day 9.5; Nkx2-5^tm1Siz/Nkx2-5^tm1Siz (more

)

Structure	Level	Pattern	Image	Note
TS15: heart	Weak		2E	Dramatically reduced expression compared to wild type.

Specimen 2F: embryonic day 9.5 (more

)

Structure	Cell Type	Level	Image	Note
TS15: cardiac muscle tissue	cardiac muscle cell	Present	2F	Authors report cardiomyocyte-specific expression.
TS15: endocardial lining		Absent	2F	No expression in endocardium.
TS15: visceral pericardium		Absent	2F	No expression in epicardium.

Specimen 2G: embryonic day 9.5; Nkx2-5^tm1Siz/Nkx2-5^tm1Siz (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS15: cardiac muscle tissue	cardiac muscle cell	Weak		2G	Dramatically reduced expression compared to wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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