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Gene Expression Data
Assay Details
Assay
Reference: J:312417 Klammer MG, et al., UNC93B1 Is Widely Expressed in the Murine CNS and Is Required for Neuroinflammation and Neuronal Injury Induced by MicroRNA let-7b. Front Immunol. 2021;12:715774
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6887612
Gene symbol: Unc93b1
Gene name: unc-93 homolog B1, TLR signaling regulator
Results
Specimen 1C WT: postnatal (more )
Note: Double labeled: green - Unc93b1; red - Rbfox3 (assay MGI:6887625).
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex neuron Present Widespread 1C WT UNC93B1 , 1C WT merged
Specimen 1C Unc93b1-/-: postnatal; Unc93b1tm1(KOMP)Vlcg/Unc93b1tm1(KOMP)Vlcg (more )
Note: Double labeled: green - Unc93b1; red - Rbfox3 (assay MGI:6887625).
Structure Level Pattern Image Note
TS28: cerebral cortex Absent 1C Unc93b1-/- merged , 1C Unc93b1-/- UNC93B1
Specimen 1D WT NeuN: postnatal (more )
Note: Double labeled: green - Unc93b1; red - Rbfox3 (assay MGI:6887625).
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex neuron Present 1D WT NeuN/UNC93B1 merged , 1D WT NeuN/UNC93B1
Specimen 1D WT GFAP: postnatal (more )
Note: Double labeled: green - Unc93b1; red - Gfap (assay MGI:6887627).
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex astrocyte Present 1D WT GFAP/UNC93B1 , 1D WT GFAP/UNC93B1 merged
Specimen 1D WT CD11b: postnatal (more )
Note: Double labeled: green - Unc93b1; red - Itgam (assay MGI:6887629).
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex microglial cell Present 1D WT Cd11b/UNC93B1 merged , 1D WT Cd11b/UNC93B1
Specimen 1D Unc93b1-/-: postnatal; Unc93b1tm1(KOMP)Vlcg/Unc93b1tm1(KOMP)Vlcg (more )
Note: Double labeled: green - Unc93b1; red - Rbfox3 (assay MGI:6887625).
Structure Level Pattern Image Note
TS28: cerebral cortex Absent 1D Unc93b1-/- merged , 1D Unc93b1-/- UNC93B1
Specimen 2C E17: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: brain Present 2C E17
Specimen 2C P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: brain Present 2C P0
Specimen 2C P12: postnatal day 12 (more )
Structure Level Pattern Image Note
TS28: brain Present 2C P12
Specimen 2C P5m: postnatal month 5 (more )
Structure Level Pattern Image Note
TS28: brain Present 2C P5m Expression gradually increased from E17-adulthood.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory