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Gene Expression Data
Assay Details
Assay
Reference: J:314587 Zhang S, et al., TMEM116 is required for lung cancer cell motility and metastasis through PDK1 signaling pathway. Cell Death Dis. 2021 Nov 16;12(12):1086
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6887375
Gene symbol: Tmem116
Gene name: transmembrane protein 116
Antibody: anti-TMEM116 (ab122663)
Assay notes: The authors did not specify which antibody was used. TMEM116 antibody (MGI:6886206) may have been used instead.
Results
Specimen 1B E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung Trace 1B E14.5 bottom , 1B E14.5 top
Specimen 1B PN1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: alveolus epithelium Present 1B PN1 bottom , 1B PN1 top
TS27: lung epithelium Present 1B PN1 bottom , 1B PN1 top
Specimen 1B Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: alveolus epithelium Present 1B Adult top , 1B Adult bottom
TS28: lung epithelium Present 1B Adult top , 1B Adult bottom
Specimen 1C CC10: postnatal (more )
Note: Double labeled: red - Tmem116; green - Scgb1a1 (assay MGI:6887381).
Structure Cell Type Level Pattern Image Note
TS28: lung epithelium club cell Present 1C CC10 Expression include Scgb1a1-positive airway Club cells.
Specimen 1C p63: postnatal (more )
Note: Double labeled: red - Tmem116; green - Trp63 (assay MGI:6887382).
Structure Cell Type Level Pattern Image Note
TS28: lung epithelium respiratory basal cell Present 1C p63 Expression include Trp63-positive basal cells.
Specimen 1C PGP9.5: postnatal (more )
Note: Double labeled: red - Tmem116; green - Uchl1 (assay MGI:6887386).
Structure Cell Type Level Pattern Image Note
TS28: lung epithelium pulmonary neuroendocrine cell Present 1C PGP9.5 Expression include Uchl1-positive neuroendocrine cells.
Specimen 1C T1-alpha: postnatal (more )
Note: Double labeled: red - Tmem116; green - Pdpn (assay MGI:6887387).
Structure Cell Type Level Pattern Image Note
TS28: lung epithelium pulmonary alveolar type 1 cell Present 1C T1-alpha Expression include Pdpn-positive alveolar type I cells.
Specimen 1C SPC: postnatal (more )
Note: Double labeled: red - Tmem116; green - Sftpc (assay MGI:6887389).
Structure Cell Type Level Pattern Image Note
TS28: lung epithelium pulmonary alveolar type 2 cell Present 1C SPC Expression include Sftpc-positive alveolar type II cells.
Specimen 1D left: postnatal; Twist2tm1(cre)Dor/Twist2+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: lung epithelium Present 1D top left , 1D bottom left
Specimen 1D right: postnatal; Twist2tm1(cre)Dor/Twist2+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: lung epithelium Present 1D top right , 1D bottom right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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