Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Pgrem1(flpo)Shah
Name:	progesterone receptor; endonuclease-mediated mutation 1, Nirao Shah
MGI ID:	MGI:6885881
Synonyms:	PRFlpo
Gene:	Pgr  Location: Chr9:8899834-8968612 bp, + strand  Genetic Position: Chr9, 2.46 cM
Alliance:	Pgrem1(flpo)Shah page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Pgrem1(flpo)Shah expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Pgr (MGI:97567)   Mutation details: Using CRISPR/Cas9-mediated homologous recombination, the 2A-Flpo was inserted into the 3'UTR in exon 8 of the Pgr gene. (J:321365)

Activity:	Tissue activity of this recombinase allele
Driver:	Pgr (mouse) Summary of all recombinase alleles driven by Pgr. Comparative matrix view of recombinase activities Alliance mouse Pgr gene page

In Mice Carrying this Mutation:

2 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pgr Mutation:	73 strains or lines available

Original:	J:321365 Knoedler JR, et al., A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior. Cell. 2022 Feb 17;185(4):654-671.e22
All:	1 reference(s)