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Gene Expression Data
Assay Details
Assay
Reference: J:45653 Matsuki M, et al., Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase). Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):1044-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6885794
Gene symbol: Loricrin
Gene name: loricrin cornified envelope precursor protein
Antibody: anti-Loricrin
Detection system: Secondary antibody coupled to colloidal gold
Assay notes: Immunoelectron microscopy.
Results
Specimen 4D: embryonic day 18.5 (more )
Note: Embedded in methacrylate.
Structure Level Pattern Image Note
TS26: epidermis granular layer Present 4D Expression is in the nuclei.
TS26: epidermis cornified layer Present 4D Expression is along the cell envelope.
Specimen 4E: embryonic day 18.5; Tgm1tm1Kfyn/Tgm1tm1Kfyn (more )
Note: Embedded in methacrylate.
Structure Level Pattern Image Note
TS26: epidermis granular layer Present 4E In this mutant expression in this layer is similar to wild-type.
TS26: epidermis cornified layer Present 4E In this mutant expression is diffuse in the cytoplasm and along the plasma membrane, and accumulated in electron-dense aggregates.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory