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Gene Expression Data
Assay Details
Assay
Reference: J:306391 Roth DM, et al., The Chromatin Regulator Ankrd11 Controls Palate and Cranial Bone Development. Front Cell Dev Biol. 2021;9:645386
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6885559
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: Anti-Ki67 (SolA15; 14-5698-82)
Detection system: Secondary antibody
Results
Specimen 5A E12.5 ctrl: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: palatal shelf Present 5A E12.5 Ankrd11ctrl
Specimen 5A E13.5 ctrl left: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf Present 5A E13.5 Ankrd11ctrl left
Specimen 5A E13.5 ctrl right: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf Present 5A E13.5 Ankrd11ctrl right
Specimen 5A E12.5 ncko: embryonic day 12.5; Ankrd11tm1c(EUCOMM)Wtsi/Ankrd11tm1c(EUCOMM)Wtsi, E2f1Tg(Wnt1-cre)2Sor/E2f1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: palatal shelf Present 5A E12.5 Ankrd11ncko Expression in this mutant is similar to controls.
Specimen 5A E13.5 ncko left: embryonic day 13.5; Ankrd11tm1c(EUCOMM)Wtsi/Ankrd11tm1c(EUCOMM)Wtsi, E2f1Tg(Wnt1-cre)2Sor/E2f1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: palatal shelf Present 5A E13.5 Ankrd11ncko left In this mutant there is a 40% decrease in mesenchymal proliferation in the oral domain compared to controls.
Specimen 5A E13.5 ncko right: embryonic day 13.5; Ankrd11tm1c(EUCOMM)Wtsi/Ankrd11tm1c(EUCOMM)Wtsi, E2f1Tg(Wnt1-cre)2Sor/E2f1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: palatal shelf Present 5A E13.5 Ankrd11ncko right In this mutant there is a 40% decrease in mesenchymal proliferation in the oral domain compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory