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Gene Expression Data
Assay Details
Assay
Reference: J:49977 Yu BD, et al., MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10632-6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6883719
Gene symbol: En1
Gene name: engrailed 1
Antibody: alpha Enhb-1
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 5A: embryonic day 10.5 (more )
Note: Flat mount of anterior somites at the level of the forelimb.
Structure Level Pattern Image Note
TS17: dermomyotome Present 5A Sharp boundaries of En1 expression were present in both the newly formed posterior somites and differentiated anterior somites throughout the trunk.
Specimen 5B: embryonic day 10.5; Kmt2atm1Sjk/Kmt2atm1Sjk (more )
Note: Flat mount of posterior somites.
Structure Level Pattern Image Note
TS17: dermomyotome Present 5B Sharp En1 expression boundaries were retained in the posterior somites of the mutant.
Specimen 5C: embryonic day 10.5; Kmt2atm1Sjk/Kmt2atm1Sjk (more )
Note: Flat mount of anterior somites at the level of the forelimb.
Structure Level Pattern Image Note
TS17: dermomyotome Present 5C Anterior somites failed to maintain sharp En1 boundaries, and positive cells were found between somites in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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