Tg(Ighm-Igh-V_V141)t11Aag
Transgene Detail
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| Symbol: |
Tg(Ighm-Igh-V_V141)t11Aag |
| Name: |
transgene insertion t11, Adriano Aguzzi |
| MGI ID: |
MGI:6883635 |
| Synonyms: |
T11, Tg(T11 H)Zbz |
| Transgene: |
Tg(Ighm-Igh-V_V141)t11Aag Location: unknown
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| Alliance: |
Tg(Ighm-Igh-V_V141)t11Aag page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The V-gene segment of the immunoglobulin heavy chain of the immunoglobulin heavy chain of the mouse B-cell hybridoma VI41 secreting a VSV-neutralizing antibody was cloned into an expression vector encoding the mouse mu-chain of allotype a. Transgenic mice express the transgenic mu-chain of the allotype a; endogenous IgM of the allotype b and immunoglobulins of other subclasses were not detected in their serum.
(J:44933)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:44933 Klein MA, et al., A crucial role for B cells in neuroinvasive scrapie [see comments]. Nature. 1997 Dec 18-25;390(6661):687-90 |
| All: |
3 reference(s) |
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Analysis Tools
