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Gene Expression Data
Assay Details
Assay
Reference: J:304771 Zhu Q, et al., Developmental trajectory of prehematopoietic stem cell formation from endothelium. Blood. 2020 Aug 13;136(7):845-856
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6874616
Gene symbol: Sox17
Gene name: SRY (sex determining region Y)-box 17
Antibody: Anti-Sox17
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen S8A Runx1+/+: embryonic day 9.5 (more )
Note: Double labeled: red - Sox17; green - Runx1 (assay MGI:6874614).
Structure Cell Type Level Pattern Image Note
TS15: dorsal aorta endothelial cell of artery Present Regionally restricted S8A Runx1+/+ Expression was detected in arterial endothelial cells. Hemogenic endothelial cells are Runx1<+>Sox17<low/->. Arterial endothelial cells are Runx1<->Sox17<+>.
Specimen S8A Runx1+/-: embryonic day 9.5; Runx1tm1Spe/Runx1+ (more )
Note: Double labeled: red - Sox17; green - Runx1 (assay MGI:6874614).
Structure Cell Type Level Pattern Image Note
TS15: dorsal aorta endothelial cell of artery Present Regionally restricted S8A Runx1+/- The ratio of Runx1<+>Sox17<low/-> Hemogenic endothelial cells versus Runx1<->Sox17<+> Arterial endothelial cells was significantly lower in E9.5 Runx1+/- embryos compared with Runx1+/+ embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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