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Gene Expression Data
Assay Details
Assay
Reference: J:188862 Lei I, et al., SWI/SNF protein component BAF250a regulates cardiac progenitor cell differentiation by modulating chromatin accessibility during second heart field development. J Biol Chem. 2012 Jul 13;287(29):24255-62
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6867812
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: Anti-Isl1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2C WT: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: outflow tract Present 2C WT E9.5
Specimen 2C Mutant: embryonic day 9.5; Arid1atm1.1Zhwa/Arid1atm1.1Zhwa, Tg(Mef2c-cre)#Blk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: outflow tract Weak 2C Mutant E9.5 Fewer Isl1-positive cells were present in the outflow tract region of the mutant heart.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory