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Gene Expression Data
Assay Details
Assay
Reference: J:312430 Fearnley S, et al., Spatiotemporal expression of IgLON family members in the developing mouse nervous system. Sci Rep. 2021 Oct 1;11(1):19536
Assay type: RNA in situ
MGI Accession ID: MGI:6864124
Gene symbol: Negr1
Gene name: neuronal growth regulator 1
Probe: Iglon4 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: habenula Present 1D
TS24: thalamic nucleus Present 1D

Specimen 2J: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: olfactory epithelium Absent 2J

Specimen 2K: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: olfactory epithelium Present Uniform 2K

Specimen 2L: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: olfactory epithelium Absent 2L

Specimen 3J: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: main olfactory bulb mitral cell layer Present 3J
TS24: main olfactory bulb prospective granule cell layer Present 3J

Specimen 3K: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: main olfactory bulb granule cell layer Present 3K
TS27: main olfactory bulb mitral cell layer Present 3K

Specimen 3L: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb granule cell layer Present 3L

Specimen 4J: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex ventricular layer Present Regionally restricted 4J Expression was detected in the apical ventricular zone.
TS24: cerebral cortex intermediate zone Weak 4J

Specimen 4K: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cortical plate Present Widespread 4K

Specimen 4L: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: cortical layer II Strong 4L
TS28: cortical layer III Strong 4L
TS28: cortical layer V Strong 4L
TS28: cortical layer VI Strong 4L

Specimen 5J: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lateral habenular nucleus Present 5J
TS24: medial habenular nucleus Present 5J
TS24: thalamic nucleus Present Regionally restricted 5J Expression was detected in the laterodorsal thalamic nucleus, the central posteromedial thalamic nucleus, the central medial thalamic nucleus, the lateroposterior thalamic nucleus, the ventral posterolateral thalamic nucleus, the medial dorsal thalamic nucleus, the paraventricular thalamic nucleus.

Specimen 5K: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: lateral habenular nucleus Present 5K
TS27: medial habenular nucleus Present 5K
TS27: thalamic nucleus Present Regionally restricted 5K Expression was detected in the laterodorsal thalamic nucleus, the central posteromedial thalamic nucleus, the central medial thalamic nucleus, the lateroposterior thalamic nucleus, the ventral posterolateral thalamic nucleus, the medial dorsal thalamic nucleus, the paraventricular thalamic nucleus.

Specimen 5L: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: lateral habenular nucleus Present 5L
TS28: medial habenular nucleus Present 5L
TS28: central medial thalamic nucleus Present 5L
TS28: lateral dorsal thalamic nucleus Present 5L
TS28: lateral posterior thalamic nucleus Present 5L
TS28: medial dorsal thalamic nucleus Present 5L
TS28: paraventricular thalamic nucleus Present 5L
TS28: ventral posterior lateral thalamic nucleus Present 5L
TS28: ventral posterior medial thalamic nucleus Present 5L

Specimen 6J: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hippocampal formation Present 6J

Specimen 6K: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: dentate gyrus Present 6K
TS27: hippocampus CA2 Present 6K
TS27: hippocampus CA3 Present 6K

Specimen 6L: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present 6L
TS28: hippocampus CA2 Present 6L
TS28: hippocampus CA3 Present 6L

Specimen 7J: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cerebellum Purkinje cell layer Weak 7J

Specimen 7K: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Present 7K , 7L

Specimen 8G: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: spinal cord Present Regionally restricted 8G Expression was enriched in the dorsal part of the spinal cord.
TS27: spinal cord gray matter Present 8G
TS27: dorsal root ganglion Present Regionally restricted 8G Expression was in a subset of neurons.

Specimen 8H: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: spinal cord Present Regionally restricted 8H Expression was enriched in the dorsal part of the spinal cord.
TS28: spinal cord gray matter Present 8H

Specimen S1J: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vomeronasal organ Absent s1J

Specimen S1K: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: vomeronasal organ Absent s1K

Specimen S1L: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: vomeronasal organ Absent s1L

Specimen S2D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: entorhinal cortex Present S2D

Specimen S3D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: eye Absent S3D

Specimen Table 1 E16: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: entorhinal cortex Strong
TS24: habenula Strong
TS24: thalamus Strong
TS24: cerebral cortex ventricular layer Moderate
TS24: hippocampal formation Moderate
TS24: cerebral cortex intermediate zone Weak
TS24: cortical plate Absent
TS24: main olfactory bulb mitral cell layer Absent
TS24: main olfactory bulb prospective glomerular layer Absent
TS24: main olfactory bulb prospective granule cell layer Absent
TS24: olfactory epithelium Absent
TS24: vomeronasal organ Absent
TS24: eye Absent No expression detected in Neuroblastic layer or Inner granular layer.

Specimen Table 1 P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: dentate gyrus Strong
TS27: cortical plate Moderate
TS27: hippocampus CA3 Moderate
TS27: main olfactory bulb mitral cell layer Moderate
TS27: olfactory epithelium Moderate
TS27: spinal cord Moderate
TS27: dorsal root ganglion Weak
TS27: habenula Weak
TS27: main olfactory bulb granule cell layer Weak
TS27: thalamus Weak
TS27: cerebellum Purkinje cell layer Absent
TS27: cerebellum internal granule cell layer Absent
TS27: cerebellum molecular layer Absent
TS27: cerebral cortex ventricular zone Absent
TS27: hippocampus CA1 Absent
TS27: main olfactory bulb glomerular layer Absent
TS27: vomeronasal organ Absent

Specimen Table 1 P15: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Strong
TS28: cerebellum internal granule cell layer Moderate
TS28: cortical layer II Moderate
TS28: cortical layer III Moderate
TS28: main olfactory bulb granule cell layer Moderate
TS28: spinal cord Moderate
TS28: cortical layer IV Weak
TS28: cortical layer V Weak
TS28: cortical layer VI Weak
TS28: dorsal root ganglion Weak
TS28: habenula Weak
TS28: hippocampus CA3 Weak
TS28: thalamus Weak
TS28: cerebellum Purkinje cell layer Absent
TS28: cerebellum molecular layer Absent
TS28: cortical layer I Absent
TS28: hippocampus CA1 Absent
TS28: main olfactory bulb glomerular layer Absent
TS28: main olfactory bulb mitral cell layer Absent
TS28: olfactory epithelium Absent
TS28: vomeronasal organ Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory