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Gene Expression Data
Assay Details
Assay
Reference: J:312430 Fearnley S, et al., Spatiotemporal expression of IgLON family members in the developing mouse nervous system. Sci Rep. 2021 Oct 1;11(1):19536
Assay type: RNA in situ
MGI Accession ID: MGI:6864123
Gene symbol: Lsamp
Gene name: limbic system-associated membrane protein
Probe: Iglon3 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex Present 1C
TS24: habenula Present 1C
TS24: thalamic nucleus Present 1C

Specimen 2G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: olfactory epithelium Present 2G

Specimen 2H: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: olfactory epithelium Present Uniform 2H

Specimen 2I: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: olfactory epithelium Absent 2I

Specimen 3G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: main olfactory bulb mitral cell layer Present 3G

Specimen 3H: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: main olfactory bulb granule cell layer Present 3H
TS27: main olfactory bulb mitral cell layer Present 3H

Specimen 3I: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb mitral cell layer Present 3I

Specimen 4G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cortical plate Present Regionally restricted 4G Expression was higher in the apical region of the cortical plate.

Specimen 4H: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cortical plate Present Widespread 4H

Specimen 4I: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: cortical layer II Strong 4I
TS28: cortical layer III Strong 4I
TS28: cortical layer V Strong 4I
TS28: cortical layer VI Strong 4I

Specimen 5G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lateral habenular nucleus Present 5G
TS24: medial habenular nucleus Present 5G
TS24: thalamic nucleus Present Regionally restricted 5G Expression was detected in the medial dorsal thalamic nucleus, and the paraventricular thalamic nucleus.

Specimen 5H: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: lateral habenular nucleus Present 5H
TS27: medial habenular nucleus Present 5H
TS27: thalamic nucleus Present Regionally restricted 5H Expression was detected in the medial dorsal thalamic nucleus, the laterodorsal thalamic nucleus, the lateroposterior thalamic nucleus, the ventral posterolateral thalamic nucleus, the central posteromedial thalamic nucleus, and the paraventricular thalamic nucleus.

Specimen 5I: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: lateral habenular nucleus Present 5I
TS28: medial habenular nucleus Present 5I
TS28: lateral dorsal thalamic nucleus Present 5I
TS28: lateral posterior thalamic nucleus Present 5I
TS28: medial dorsal thalamic nucleus Present 5I
TS28: paraventricular thalamic nucleus Present 5I
TS28: ventral posterior lateral thalamic nucleus Present 5I
TS28: ventral posterior medial thalamic nucleus Present 5I

Specimen 6G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hippocampal formation Present 6G

Specimen 6H: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: dentate gyrus Present 6H
TS27: hippocampus CA1 Present 6H
TS27: hippocampus CA3 Present 6H

Specimen 6I: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present 6I
TS28: hippocampus CA1 Present 6I
TS28: hippocampus CA3 Present 6I

Specimen 7G: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cerebellum internal granule cell layer Present 7G
TS27: cerebellum Purkinje cell layer Weak 7G

Specimen 7H: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Present 7H , 7I
TS28: cerebellum Purkinje cell layer Weak 7H , 7I

Specimen 8E: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: spinal cord gray matter Present Widespread 8E
TS27: spinal cord Strong Regionally restricted 8E High expression was detected in the ventral part of the spinal cord containing motor neurons.
TS27: dorsal root ganglion Present 8E Expression was in the majority of neurons.

Specimen 8F: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: spinal cord gray matter Present Widespread 8F
TS28: dorsal root ganglion Present 8F Expression was in the majority of neurons.

Specimen S1G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vomeronasal organ Present Regionally restricted s1G At E16, expression was detected more basally in the vomeronasal organ.

Specimen S1H: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: vomeronasal organ Present Uniform s1H

Specimen S1I: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: vomeronasal organ Absent s1I

Specimen S2C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: entorhinal cortex Present S2C

Specimen S3C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: retina inner nuclear layer Present S3C
TS24: retina layer Present Regionally restricted S3C Expression was detected in the ganglion cell layer and the neuroblastic cell layer.
TS24: lens Strong S3C

Specimen Table 1 E16: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: eye Strong Regionally restricted High expression was detected in Neuroblastic layer and Inner granular layer.
TS24: cortical plate Strong
TS24: entorhinal cortex Strong
TS24: main olfactory bulb mitral cell layer Strong
TS24: habenula Moderate
TS24: hippocampal formation Moderate
TS24: olfactory epithelium Moderate
TS24: thalamus Moderate
TS24: vomeronasal organ Moderate
TS24: cerebral cortex intermediate zone Absent
TS24: cerebral cortex ventricular layer Absent
TS24: main olfactory bulb prospective glomerular layer Absent
TS24: main olfactory bulb prospective granule cell layer Absent

Specimen Table 1 P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cortical plate Strong
TS27: dorsal root ganglion Strong
TS27: hippocampus CA1 Strong
TS27: hippocampus CA3 Strong
TS27: main olfactory bulb granule cell layer Strong
TS27: main olfactory bulb mitral cell layer Strong
TS27: olfactory epithelium Strong
TS27: spinal cord Strong
TS27: vomeronasal organ Strong
TS27: cerebellum internal granule cell layer Moderate
TS27: dentate gyrus Moderate
TS27: habenula Moderate
TS27: thalamus Moderate
TS27: cerebellum Purkinje cell layer Weak
TS27: cerebellum molecular layer Absent
TS27: cerebral cortex ventricular zone Absent
TS27: main olfactory bulb glomerular layer Absent

Specimen Table 1 P15: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: cortical layer II Strong
TS28: cortical layer III Strong
TS28: cortical layer IV Strong
TS28: cortical layer V Strong
TS28: cortical layer VI Strong
TS28: dentate gyrus Strong
TS28: dorsal root ganglion Strong
TS28: hippocampus CA1 Strong
TS28: hippocampus CA3 Strong
TS28: main olfactory bulb mitral cell layer Strong
TS28: spinal cord Strong
TS28: cerebellum internal granule cell layer Moderate
TS28: habenula Moderate
TS28: thalamus Moderate
TS28: cerebellum Purkinje cell layer Weak
TS28: cerebellum molecular layer Absent
TS28: cortical layer I Absent
TS28: main olfactory bulb glomerular layer Absent
TS28: main olfactory bulb granule cell layer Absent
TS28: olfactory epithelium Absent
TS28: vomeronasal organ Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory