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Gene Expression Data
Assay Details
Assay
Reference: J:137216 Fujino T, et al., cpg15 and cpg15-2 constitute a family of activity-regulated ligands expressed differentially in the nervous system to promote neurite growth and neuronal survival. J Comp Neurol. 2008 Apr 10;507(5):1831-45
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6863925
Gene symbol: Nrn1l
Gene name: neuritin 1-like
Antibody: anti-CPG15-2
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 5A: postnatal week 8-12 (more )
Note: Double labeled: magenta - cpg15-2 (Nrn1l); green - DAPI.
Structure Level Pattern Image Note
TS28: retina outer plexiform layer Present 5A CPG15-2 (left) , 5A CPG15-2 (right)
TS28: retina inner nuclear layer Present Regionally restricted 5A CPG15-2 (left) , 5A CPG15-2 (right) Expression in a fiber type spanning inner nuclear and inner plexiform layers.
TS28: retina inner plexiform layer Present Regionally restricted 5A CPG15-2 (left) , 5A CPG15-2 (right) Expression in a fiber type spanning inner nuclear and inner plexiform layers.
TS28: retina ganglion cell layer Absent 5A CPG15-2 (left) , 5A CPG15-2 (right) Low or undetectable expression in ganglion cell layer and outer nuclear layer.
TS28: retina outer nuclear layer Absent 5A CPG15-2 (left) , 5A CPG15-2 (right) Low or undetectable expression in ganglion cell layer and outer nuclear layer.

Specimen 5B: postnatal week 8-12 (more )
Note: Double labeled: magenta - cpg15-2 (Nrn1l); green - PKCalpha (Prkca assay MGI:6863927).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 5B CPG15-2 , 5B merged Expression in rod bipolar cells, with ~90% of fiber-like expression colocalized with PKCalpha (Prkca) in axons. Expression also in fibers negative fo Prkca expression, likely cone bipolar cells.
TS28: retina inner plexiform layer Present Regionally restricted 5B CPG15-2 , 5B merged Expression in rod bipolar cells, with ~90% of fiber-like expression colocalized with PKCalpha (Prkca) in axons. Expression also in fibers negative fo Prkca expression, likely cone bipolar cells.
TS28: retina outer plexiform layer Present Regionally restricted 5B CPG15-2 , 5B merged Expression in rod bipolar cells, with ~90% of fiber-like expression colocalized with PKCalpha (Prkca) in axons. Expression also in fibers negative fo Prkca expression, likely cone bipolar cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory