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Gene Expression Data
Assay Details
Assay
Reference: J:314664 Harada Y, et al., Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module. Nat Commun. 2021 Nov 12;12(1):6562
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6860530
Gene symbol: Ascl1
Gene name: achaete-scute family bHLH transcription factor 1
Antibody: Anti-MASH1 (556604; 24B72D11.1)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 7d Hey1+/+: embryonic day 14.5 (more )
Note: Double labeled: green - Ascl1; red - Sox2 (assay MGI:6860525).
Structure Level Pattern Image Note
TS22: lateral ganglionic eminence Present Regionally restricted 7d Hey1+/+
Specimen 7d Hey1-/-: embryonic day 14.5; Hey1tm1Kkb/Hey1tm1Kkb (more )
Note: Double labeled: green - Ascl1; red - Sox2 (assay MGI:6860525).
Structure Level Pattern Image Note
TS22: lateral ganglionic eminence Strong Regionally restricted 7d Hey1-/- Proportion of Ascl1-expressing cells within Sox2-expressing cells in dorsal lateral ganglionic eminence (dLGE) was significantly higher in knockout than in control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory