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Gene Expression Data
Assay Details
Assay
Reference: J:226722 Shen J, et al., Expression Analysis of DGKK during External Genitalia Formation. J Urol. 2015 Dec;194(6):1728-36
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6860336
Gene symbol: Dgkk
Gene name: diacylglycerol kinase kappa
Antibody: Anti-Dgkk
Results
Specimen 1A: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: urethral plate epithelium of male Present 1A Expression was detected in the membrane and cytoplasm of epithelial cells of solid urethral plate.

Specimen 1B: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: genital tubercle epithelium Present Regionally restricted 1B Expression was detected in the suprabasal layers of stratified squamous epithelium in the urethral groove lumen.
TS24: genital tubercle of male Present Regionally restricted 1B Expression was detected in epidermal cells, as well as cells scattered throughout the mesenchyme, which probably represent developing vasculature. Undifferentiated epithelial cells of preputial lamina were immunonegative.

Specimen 1C: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: genital tubercle epithelium Present Regionally restricted 1C Expression was detected in the suprabasal layers of stratified squamous epithelium in the urethral groove lumen.
TS26: genital tubercle of male Present Regionally restricted 1C Expression was detected in epidermal cells, as well as cells scattered throughout the mesenchyme, which probably represent developing vasculature. Undifferentiated epithelial cells of preputial lamina were immunonegative.

Specimen 2A: postnatal day 10 (more )
Note: Distal section of external genitalia.
Structure Level Pattern Image Note
TS28: prepuce of male Strong Regionally restricted 2A , 2A' Expression was strong in the membrane and cytoplasm of suprabasal layers of preputial groove epithelium and weak in the basal layer.

Specimen 2B: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: prepuce of male Present Regionally restricted 2B , 2B' Expression was detected in the epithelium bounding preputial space. Within the preputial epithelium distinct staining was observed in the basal and suprabasal layers.
TS28: preputial gland of male Present Regionally restricted 2B , 2B' Expression was detected in the epithelium of preputial gland ducts.
TS28: hair follicle of male prepuce Present 2B , 2B'

Specimen 2C: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: prepuce of male Present Regionally restricted 2C , 2C' Expression was detected in the epithelium bounding preputial space. Within the preputial epithelium distinct staining was observed in the basal and suprabasal layers.
TS28: preputial gland of male Present Regionally restricted 2C' , 2C Expression was detected in the epithelium of preputial gland ducts.
TS28: hair follicle of male prepuce Present 2C' , 2C

Specimen 2D: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: prepuce of male Present Regionally restricted 2D' , 2D Transverse section of the preputial space reveals dorsal and lateral epithelial processes extending peripherally. The epithelium forming this dorsoventrally flattened preputial space was immunopositive.

Specimen 2E: postnatal day 10 (more )
Note: Proximal section of external genitalia.
Structure Level Pattern Image Note
TS28: epithelium of penile urethra Present Regionally restricted 2E , 2E' Expression was mostly in the suprabasal layers of the urethral epithelium.

Specimen 3C: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: penis epithelium Strong Regionally restricted 3C' , 3C Strong expression was detected in differentiated suprabasal layers of epithelium.

Specimen 5A: embryonic day 18.0 (more )
Note: Distal section of male genital tubercle.
Structure Level Pattern Image Note
TS26: urethral fold of male Present 5A

Specimen 5B: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: urethral fold of male Present 5B

Specimen 5C: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: urethral fold of male Present 5C

Specimen 5D: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: urethra of male Present 5D

Specimen 5E: embryonic day 18.0 (more )
Note: Proximal section of male genital tubercle.
Structure Level Pattern Image Note
TS26: urethra of male Present 5E

Specimen 5F: embryonic day 18.0 (more )
Note: Distal section of female genital tubercle.
Structure Level Pattern Image Note
TS26: urethral fold of female Present 5F

Specimen 5G: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: urethral fold of female Present 5G

Specimen 5H: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: urethral fold of female Present 5H

Specimen 5I: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: urethra of female Present 5I

Specimen 5J: embryonic day 18.0 (more )
Note: Proximal section of female genital tubercle.
Structure Level Pattern Image Note
TS26: urethra of female Present 5J


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory