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Gene Expression Data
Assay Details
Assay
Reference: J:316636 Fabritius AL, et al., Neuronal ceroid lipofuscinosis genes, CLN2, CLN3 and CLN5 are spatially and temporally co-expressed in a developing mouse brain. Exp Mol Pathol. 2014 Dec;97(3):484-91
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6857770
Gene symbol: Cln5
Gene name: ceroid-lipofuscinosis, neuronal 5
Antibody: Anti-CLN5
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3A-9: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebellum external granule cell layer Strong Regionally restricted 3A9 Strong expression was detected in the inner migratory zone of the external granule layer.
TS26: cerebellum white matter Present 3A9
TS26: facial nucleus Present 3A9

Specimen 3A-10: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebellum external granule cell layer Strong Regionally restricted 3A10 Strong expression was detected in the inner migratory zone of the external granule layer.

Specimen 3A-11: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present 3A11
TS28: cerebellum Purkinje cell layer Weak 3A11

Specimen 3A-12: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 3A12
TS28: cerebellum internal granule cell layer Present 3A12

Specimen 3B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: pons Present 3B CLN5 Expression was detected in large neurons localized in the pons region.

Specimen 4A3: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: CA2 pyramidal cell layer Strong 4A3
TS28: CA3 pyramidal cell layer Strong 4A4 , 4A3

Specimen 4B3: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Present 4B3 , 4B4

Specimen 4C3: postnatal day 24 (more )
Structure Level Pattern Image Note
TS28: CA2 pyramidal cell layer Strong 4C3
TS28: CA3 pyramidal cell layer Strong 4C4 , 4C3

Specimen 4D3: postnatal day 24 (more )
Structure Level Pattern Image Note
TS28: CA3 pyramidal cell layer Strong 4D4 , 4D3

Specimen not shown: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: hippocampus CA2 Strong Expression was in pyramidal cells.
TS27: hippocampus CA3 Strong Expression was in pyramidal cells.

Specimen not shown: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Strong Expression was detected in large neurons.
TS28: hippocampus Strong Expression was detected in large neurons.
TS28: hypothalamus Present
TS28: paraventricular thalamic nucleus Present
TS28: retrosplenial granular cortex Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory