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Gene Expression Data
Assay Details
Assay
Reference: J:316636 Fabritius AL, et al., Neuronal ceroid lipofuscinosis genes, CLN2, CLN3 and CLN5 are spatially and temporally co-expressed in a developing mouse brain. Exp Mol Pathol. 2014 Dec;97(3):484-91
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6857768
Gene symbol: Cln3
Gene name: CLN3 lysosomal/endosomal transmembrane protein, battenin
Antibody: Anti-CLN3
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3A-5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebellum external granule cell layer Strong Regionally restricted 3A5 Strong expression was detected in the inner migratory zone of the external granule layer.
TS26: cerebellum white matter Present 3A5
TS26: facial nucleus Present 3A5

Specimen 3A-6: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebellum external granule cell layer Strong Regionally restricted 3A6 Strong expression was detected in the inner migratory zone of the external granule layer.

Specimen 3A-7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present 3A7
TS28: cerebellum Purkinje cell layer Weak 3A7

Specimen 3A-8: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 3A8
TS28: cerebellum internal granule cell layer Present 3A8

Specimen 3B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: pons Present 3B CLN3 Expression was detected in large neurons localized in the pons region.

Specimen 4A2: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: CA2 pyramidal cell layer Strong 4A2
TS28: CA3 pyramidal cell layer Strong 4A2

Specimen 4B2: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Present 4B2

Specimen 4C2: postnatal day 24 (more )
Structure Level Pattern Image Note
TS28: CA2 pyramidal cell layer Strong 4C2
TS28: CA3 pyramidal cell layer Strong 4C2

Specimen 4D2: postnatal day 24 (more )
Structure Level Pattern Image Note
TS28: CA3 pyramidal cell layer Strong 4D2

Specimen not shown: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: hippocampus CA2 Strong Expression was in pyramidal cells.
TS27: hippocampus CA3 Strong Expression was in pyramidal cells.

Specimen not shown: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Strong Expression was detected in large neurons.
TS28: hippocampus Strong Expression was detected in large neurons.
TS28: hypothalamus Present
TS28: paraventricular thalamic nucleus Present
TS28: retrosplenial granular cortex Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory