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Gene Expression Data
Assay Details
Assay
Reference: J:44602 Smidt MP, et al., A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons. Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13305-10
Assay type: RNA in situ
MGI Accession ID: MGI:6857668
Gene symbol: Pitx3
Gene name: paired-like homeodomain transcription factor 3
Probe: Ptx3 probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4A/B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted 4A/B Expression is in a layer of postmitotic cells in the mesencephalon lining the mesencephalic flexure.

Specimen 4C/D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain Present Regionally restricted 4C/D Expression is in a thick layer of mesencephalic dopaminergic neurons as part of the tegmentum.
TS20: pituitary gland Present 4C/D
TS20: tongue Present 4C/D

Specimen 4E/F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: Rathke's pouch Absent 4E/F
TS17: brain Absent 4E/F

Specimen 4G/H: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted 4G/H Expression is in the tgemental region.
TS19: midbrain marginal layer Present Regionally restricted 4G/H Expression is ventral in mesencephalic dopaminergic neurons.

Specimen 4I/J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: midbrain tegmentum Present Regionally restricted 4I/J Expression is in a central region of the ventral tegmentum.

Specimen 4K/L: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: midbrain tegmentum Present Regionally restricted 4K/L Expression is in the ventral tegmentum.
TS23: cartilage Present 4K/L
TS23: tongue Present 4K/L

Specimen not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: head Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory