Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Atoh1em1(cre)Zyliu
Name:	atonal bHLH transcription factor 1; endonuclease-mediated mutation 1, Zhiyong Liu
MGI ID:	MGI:6856836
Synonyms:	Atoh13*HA-P2A-Cre
Gene:	Atoh1  Location: Chr6:64706109-64708229 bp, + strand  Genetic Position: Chr6, 30.03 cM
Alliance:	Atoh1em1(cre)Zyliu page

Strain of Origin:

C57BL/6 x DBA/2

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Atoh1em1(cre)Zyliu expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Atoh1 (MGI:104654)   Mutation details: Using CRISPR/Cas9 technology, three hemagglutinin (HA) tags, a P2A ribosomal skip cleavage peptide sequence, and a cre recombinase were inserted immediately before the stop codon of the atonal bHLH transcription factor 1 (Atoh1) gene. (J:326361)

Activity:	Tissue activity of this recombinase allele
Driver:	Atoh1 (mouse) Summary of all recombinase alleles driven by Atoh1. Comparative matrix view of recombinase activities Alliance mouse Atoh1 gene page

In Mice Carrying this Mutation:

125 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atoh1 Mutation:	36 strains or lines available

Original:	J:326361 Li S, et al., Fate-mapping analysis of cochlear cells expressing Atoh1 mRNA via a new Atoh1(3*HA-P2A-Cre) knockin mouse strain. Dev Dyn. 2022 Jul;251(7):1156-1174
All:	2 reference(s)