Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	C1ql2em1(cre)Gfng
Name:	complement component 1, q subcomponent-like 2; endonuclease-mediated mutation 1, Guoping Feng
MGI ID:	MGI:6856619
Synonyms:	C1QL2-IRES-Cre
Gene:	C1ql2  Location: Chr1:120268312-120270903 bp, + strand  Genetic Position: Chr1, 52.68 cM
Alliance:	C1ql2em1(cre)Gfng page

Strain of Origin:

C57BL/6NTac

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   C1ql2em1(cre)Gfng expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse C1ql2 (MGI:3032521)   Mutation details: An IRES-Cre-pA cassette was introduced immediately after the stop codon of the mouse C1ql2 gene in C57BL/6NTac embryos using CRISPR/Cas9 methodologies. (J:317610)

Activity:	Tissue activity of this recombinase allele
Driver:	C1ql2 (mouse) Summary of all recombinase alleles driven by C1ql2. Comparative matrix view of recombinase activities Alliance mouse C1ql2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any C1ql2 Mutation:	11 strains or lines available

Original:	J:317610 Roy DS, et al., Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models. Neuron. 2021 Aug 18;109(16):2590-2603.e13
All:	2 reference(s)