Gene Expression Data
Assay Details
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Assay
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Reference:
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J:316709
Wong CO, et al., Diminished MTORC1-Dependent JNK Activation Underlies the Neurodevelopmental Defects Associated with Lysosomal Dysfunction. Cell Rep. 2015 Sep 29;12(12):2009-20
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6856609
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Gene symbol:
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Mapk8
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Gene name:
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mitogen-activated protein kinase 8
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Antibody:
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anti-JNK
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
S4H:
embryonic day 19.5
(more  )
Specimen
S4H:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 19.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Specimen
S4I:
embryonic day 19.5
(more )
Specimen
S4I:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 19.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Specimen
S4J:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Cln3tm1.1Mem/Cln3tm1.1Mem
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Age:
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embryonic day 19.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: corpus callosum |
Present |
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S4J
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Total JNK expression not changed compared with wild type.
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Specimen
S4K:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Cln3tm1.1Mem/Cln3tm1.1Mem
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Age:
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embryonic day 19.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: brain white matter |
Present |
Regionally restricted |
S4K
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Expression in axonal tracts. Total JNK expression not changed compared with wild type
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Analysis Tools