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Gene Expression Data
Assay Details
Assay
Reference: J:316709 Wong CO, et al., Diminished MTORC1-Dependent JNK Activation Underlies the Neurodevelopmental Defects Associated with Lysosomal Dysfunction. Cell Rep. 2015 Sep 29;12(12):2009-20
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6856608
Gene symbol: Mapk8
Gene name: mitogen-activated protein kinase 8
Antibody: anti-pJNK
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 6G: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: corpus callosum Present 6G
Specimen 6H: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: brain white matter Present Regionally restricted 6H Expression in axonal tracts.
Specimen 6I: embryonic day 19.5; Cln3tm1.1Mem/Cln3tm1.1Mem (more )
Structure Level Pattern Image Note
TS26: corpus callosum Weak 6I Lower expression levels in the corpus callosum compared with wild type.
Specimen 6J: embryonic day 19.5; Cln3tm1.1Mem/Cln3tm1.1Mem (more )
Structure Level Pattern Image Note
TS26: brain white matter Weak Regionally restricted 6J
TS26: brain commissure Weak Regionally restricted 6J Decreased expression especially striking in commissures adjacent to corpus callosum.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory