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Gene Expression Data
Assay Details
Assay
Reference: J:317048 Xiong Z, et al., Transmission of ER stress response by ATF6 promotes endochondral bone growth. J Orthop Surg Res. 2015 Sep 15;10:141
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6852680
Gene symbol: Atf6
Gene name: activating transcription factor 6
Antibody: anti-ATF6
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2b: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: epiphyseal plate hypertrophic zone Present Regionally restricted 2b Prominent nuclear expression throughout growth plate chondrocytes in both proliferating and hypertrophic zones.
TS23: epiphyseal plate proliferative zone Present Regionally restricted 2b Prominent nuclear expression throughout growth plate chondrocytes in both proliferating and hypertrophic zones.
TS23: tibia Present Regionally restricted 2b Prominent nuclear expression throughout growth plate chondrocytes in both proliferating and hypertrophic zones.

Specimen 2c: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epiphyseal plate hypertrophic zone Present Regionally restricted 2c Prominent nuclear expression throughout growth plate chondrocytes in both proliferating and hypertrophic zones.
TS25: epiphyseal plate proliferative zone Present Regionally restricted 2c Prominent nuclear expression throughout growth plate chondrocytes in both proliferating and hypertrophic zones.
TS25: tibia Present Regionally restricted 2c Prominent nuclear expression throughout growth plate chondrocytes in both proliferating and hypertrophic zones.

Specimen 2d: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: epiphyseal plate hypertrophic zone Present Regionally restricted 2d Prominent nuclear expression throughout growth plate chondrocytes in both proliferating and hypertrophic zones.
TS27: epiphyseal plate proliferative zone Present Regionally restricted 2d Prominent nuclear expression throughout growth plate chondrocytes in both proliferating and hypertrophic zones.
TS27: tibia Present Regionally restricted 2d Prominent nuclear expression throughout growth plate chondrocytes in both proliferating and hypertrophic zones.

Specimen 2e: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: epiphyseal plate hypertrophic zone Present Regionally restricted 2e Prominent nuclear expression throughout growth plate chondrocytes in both proliferating and hypertrophic zones.
TS28: epiphyseal plate proliferative zone Present Regionally restricted 2e Prominent nuclear expression throughout growth plate chondrocytes in both proliferating and hypertrophic zones.
TS28: tibia Present Regionally restricted 2e Prominent nuclear expression throughout growth plate chondrocytes in both proliferating and hypertrophic zones.

Specimen 2g: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: epiphyseal plate hypertrophic zone Strong Regionally restricted 2g Especially highly expressed in hypertrophic chondrocyte stage

Specimen 2h: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epiphyseal plate hypertrophic zone Strong Regionally restricted 2h Especially highly expressed in hypertrophic chondrocyte stage

Specimen 2i: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: epiphyseal plate hypertrophic zone Strong Regionally restricted 2i Especially highly expressed in hypertrophic chondrocyte stage

Specimen 2j: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: epiphyseal plate hypertrophic zone Strong Regionally restricted 2j Especially highly expressed in hypertrophic chondrocyte stage


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory