F2r In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:71309 Griffin CT, et al., A role for thrombin receptor signaling in endothelial cells during embryonic development. Science. 2001 Aug 31;293(5535):1666-70
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:6850614
Gene symbol:	F2r
Gene name:	coagulation factor II thrombin receptor

Reporter:	lacZ
	Direct Detection

Results

Specimen 2A: embryonic day 9.5; F2r^tm1.1Cgh/F2r^tm1.1Cgh (more

)

Structure	Level	Pattern	Image	Note
TS15: endocardial lining	Present		2A
TS15: blood vessel	Present	Regionally restricted	2A	Expression is in the endothelium of great and small vessels and in occasional round cells adhering to the vessel wall.
TS15: cardiovascular system endothelium	Present	Regionally restricted	2A	Expression is in the endothelium of great and small vessels and in occasional round cells adhering to the vessel wall.
TS15: septum transversum	Present	Regionally restricted	2A	Expression is in a subset of mesenchymal-appearing cells.

Specimen 2B: embryonic day 9.5; F2r^tm1.1Cgh/F2r^tm1.1Cgh (more

)

Structure	Level	Pattern	Image	Note
TS15: blood vessel	Present	Regionally restricted	2B	Expression is in the endothelium of great and small vessels and in occasional round cells adhering to the vessel wall.
TS15: cardiovascular system endothelium	Present	Regionally restricted	2B	Expression is in the endothelium of great and small vessels and in occasional round cells adhering to the vessel wall.

Specimen 2C: embryonic day 9.5; F2r^tm1.1Cgh/F2r^tm1.1Cgh (more

)

Structure	Level	Pattern	Image	Note
TS15: endocardial lining	Present		2C

Specimen 2D: embryonic day 9.5; F2r^tm1.1Cgh/F2r^tm1.1Cgh (more

)

Structure	Level	Pattern	Image	Note
TS15: blood vessel	Present	Regionally restricted	2D	Expression is in the endothelium of great and small vessels and in occasional round cells adhering to the vessel wall.
TS15: cardiovascular system endothelium	Present	Regionally restricted	2D	Expression is in the endothelium of great and small vessels and in occasional round cells adhering to the vessel wall.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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