Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:207051
Carlisle FA, et al., Pitpnm1 is expressed in hair cells during development but is not required for hearing. Neuroscience. 2013 Jun 29;248C:620-625
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:6849982
|
|
Gene symbol:
|
Pitpnm1
|
|
Gene name:
|
phosphatidylinositol transfer protein, membrane-associated 1
|
|
|
Results
|
Specimen
1A:
(close  )
|
Genetic Background:
|
C57BL/6J-Tyrc-Btlr
|
|
Mutant Allele(s):
|
Tyrc-Btlr/Tyrc-Btlr
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
10% Formalin
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: organ of Corti |
Weak |
Regionally restricted |
1A
|
Faint expression in inner hair cells.
|
Specimen
P0 not shown:
(close )
|
Genetic Background:
|
C57BL/6J-Tyrc-Btlr
|
|
Mutant Allele(s):
|
Tyrc-Btlr/Tyrc-Btlr
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
10% Formalin
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: organ of Corti |
Present |
Regionally restricted |
|
Expression generally identical to that seen at E18.5 but more clear and well established.
|
Specimen
P3 not shown:
(close )
|
Genetic Background:
|
C57BL/6J-Tyrc-Btlr
|
|
Mutant Allele(s):
|
Tyrc-Btlr/Tyrc-Btlr
|
|
Age:
|
postnatal day 3
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
10% Formalin
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: organ of Corti |
Strong |
Regionally restricted |
|
Strong expression in all hair cells.
|
Specimen
1B:
(close )
|
Genetic Background:
|
C57BL/6J-Tyrc-Btlr
|
|
Mutant Allele(s):
|
Tyrc-Btlr/Tyrc-Btlr
|
|
Age:
|
postnatal day 5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
10% Formalin
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Strong |
Regionally restricted |
1B
|
Heavy expression in all inner hair cells; steep gradient of expression in outer hair cells at base.
|
Specimen
1C:
(close )
|
Genetic Background:
|
C57BL/6J-Tyrc-Btlr
|
|
Mutant Allele(s):
|
Tyrc-Btlr/Tyrc-Btlr
|
|
Age:
|
postnatal day 5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
10% Formalin
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
1C
|
Expression in all hair cells at apex. Expression in outer hair cells similar to that seen at P3.
|
Specimen
1D:
(close )
|
Genetic Background:
|
C57BL/6J-Tyrc-Btlr
|
|
Mutant Allele(s):
|
Tyrc-Btlr/Tyrc-Btlr
|
|
Age:
|
postnatal day 5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
10% Formalin
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
1D
|
Expression only in inner hair cells at base. Essentially no expression in outer hair cells.
|
Specimen
1E:
(close )
|
Genetic Background:
|
C57BL/6J-Tyrc-Btlr
|
|
Mutant Allele(s):
|
Tyrc-Btlr/Tyrc-Btlr
|
|
Age:
|
postnatal day 5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
10% Formalin
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: crista ampullaris |
Moderate |
Regionally restricted |
1E
|
Moderate levels of expression in vestibular hair cells and supporting cells of crista from E18.5; maintained at fairly constant level up to P5.
|
| TS28: inner ear vestibular component |
Moderate |
Regionally restricted |
1E
|
Moderate levels of expression in vestibular hair cells and supporting cells of crista from E18.5; maintained at fairly constant level up to P5.
|
Specimen
1F:
postnatal week 9
(more  )
Specimen
1F:
(close )
|
Genetic Background:
|
involves: C57BL/6J * C57BL/6N
|
|
Age:
|
postnatal week 9
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
10% Formalin
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Weak |
Regionally restricted |
1F
|
Faint expression only in inner hair cells.
|
Specimen
1G:
postnatal week 9
(more )
Specimen
1G:
(close )
|
Genetic Background:
|
involves: C57BL/6J * C57BL/6N
|
|
Age:
|
postnatal week 9
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
10% Formalin
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Weak |
Regionally restricted |
1G
|
Faint expression only in inner hair cells.
|
Specimen
1H:
postnatal week 9
(more )
Specimen
1H:
(close )
|
Genetic Background:
|
involves: C57BL/6J * C57BL/6N
|
|
Age:
|
postnatal week 9
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
10% Formalin
|
|
Embedding:
|
Paraffin
|
Specimen
2A:
(close )
|
Genetic Background:
|
C57BL/6J-Tyrc-Btlr
|
|
Mutant Allele(s):
|
Tyrc-Btlr/Tyrc-Btlr
|
|
Age:
|
postnatal day 4
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
10% Formalin
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: organ of Corti |
Present |
Regionally restricted |
2A
|
Expression in hair cells.
|
Specimen
2B:
(close )
|
Genetic Background:
|
C57BL/6J-Tyrc-Btlr
|
|
Mutant Allele(s):
|
Tyrc-Btlr/Tyrc-Btlr
|
|
Age:
|
postnatal day 4
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
10% Formalin
|
|
Embedding:
|
Paraffin
|
Specimen
2C:
(close )
Specimen
2D:
(close )
|
Analysis Tools