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Gene Expression Data
Assay Details
Assay
Reference: J:52289 Lee YJ, et al., A possible role for the high mobility group box transcription factor Tcf-4 in vertebrate gut epithelial cell differentiation. J Biol Chem. 1999 Jan 15;274(3):1566-72
Assay type: RNA in situ
MGI Accession ID: MGI:6845121
Gene symbol: Tcf7l2
Gene name: transcription factor 7 like 2, T cell specific, HMG box
Probe: mTcf-4B probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3 E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: embryo Absent 3_E11.5 Expression first detected between E11.5 and E13.5.
Specimen 3 E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: thalamus Present 3_E13.5
TS21: midbrain roof plate Present 3_E13.5 Extension of expression into roof of midbrain detected as early as E13.5.
Specimen 3 E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: thalamus Strong 3_E15.5 Expression in diencephalon and mesencephalon becomes more prominent by E15.5. Predominent expression in thalamus
TS23: midbrain roof plate Present Regionally restricted 3_E15.5 Characteristic pattern of expression in posterior portion of roof of mesencehphalon, separated from expression in thalamus.
Specimen 3 E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: thalamus Present 3_E18 Expression persists at least until E18.
TS26: midbrain roof plate Present 3_E18 Expression persists at least until E18.
Specimen 4B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: intestine epithelium Present 4B Expression confined to epithelial lining of gastrointestinal tract.
Specimen 4C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: stomach epithelium Present Patchy 4C
Specimen 4D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: intestine epithelium Present Patchy 4D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory