Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:171231 Bouwman P, et al., Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression. J Pathol. 2011 May;224(1):10-21
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6843027
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-caspase-3
Detection system:	Secondary antibody coupled to horseradish peroxidase
Assay notes:	This antibody recognizes the cleaved form of the protein.

Results

Specimen 3B Palb2^GT/+;p53^+/-: embryonic day 10.5; Palb2^{Gt(CG0691)Wtsi}/Palb2⁺, Trp53^tm1.1Brn/Trp53⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Absent		3B Palb2^GT/+;p53^+/-

Specimen 3B Palb2^GT/GT;p53^+/-: embryonic day 10.5; Palb2^{Gt(CG0691)Wtsi}/Palb2^{Gt(CG0691)Wtsi}, Trp53^tm1.1Brn/Trp53⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		3B Palb2^GT/GT;p53^+/-

Specimen 3B Palb2^GT/+;p53^-/-: embryonic day 10.5; Palb2^{Gt(CG0691)Wtsi}/Palb2⁺, Trp53^tm1.1Brn/Trp53^tm1.1Brn (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Absent		3B Palb2^GT/+;p53^-/-

Specimen 3B Palb2^GT/GT;p53^-/-: embryonic day 10.5; Palb2^{Gt(CG0691)Wtsi}/Palb2^{Gt(CG0691)Wtsi}, Trp53^tm1.1Brn/Trp53^tm1.1Brn (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		3B Palb2^GT/GT;p53^-/-

Specimen not shown Palb2^GT/GT: embryonic day 8.5; Palb2^{Gt(CG0691)Wtsi}/Palb2^{Gt(CG0691)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS13: embryo	Strong

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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