About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:46856 Saucedo-Cardenas O, et al., Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):4013-8
Assay type: RNA in situ
MGI Accession ID: MGI:6842959
Gene symbol: Pitx3
Gene name: paired-like homeodomain transcription factor 3
Probe: Ptx3 probe
Probe preparation: Antisense RNA
Results
Specimen 4C +/+: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: midbrain Strong Regionally restricted 4C +/+ Expression is ventral in mesencephalic dopaminergic progenitor cells.

Specimen 4C -/-: embryonic day 11.5; Nr4a2tm1Omc/Nr4a2tm1Omc (more )
Structure Level Pattern Image Note
TS19: midbrain Strong Regionally restricted 4C -/- Expression in this mutant is the same as in wild-type.

Specimen 5A: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: midbrain Present Regionally restricted 5A Expression is ventral in mature dopaminergic neurons.

Specimen 5B: postnatal newborn; Nr4a2tm1Omc/Nr4a2tm1Omc (more )
Structure Level Pattern Image Note
TS27: midbrain Trace Single cells 5B Expression is in a few scattered cells in the ventral mid-brain.

Specimen 5C: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: midbrain Present Regionally restricted 5C Expression is ventral in mature dopaminergic neurons.

Specimen 5D: postnatal newborn; Nr4a2tm1Omc/Nr4a2tm1Omc (more )
Structure Level Pattern Image Note
TS27: midbrain Trace Single cells 5D Expression is in a few scattered cells in the ventral mid-brain.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory