Gene Expression Data
Assay Details
Assay
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Reference:
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J:46856
Saucedo-Cardenas O, et al., Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):4013-8
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6842959
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Gene symbol:
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Pitx3
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Gene name:
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paired-like homeodomain transcription factor 3
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Probe:
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Ptx3 probe
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Probe preparation:
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Antisense RNA
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Results
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Specimen
4C +/+:
embryonic day 11.5
(more )
Specimen
4C +/+:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS19: midbrain |
Strong |
Regionally restricted |
4C +/+
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Expression is ventral in mesencephalic dopaminergic progenitor cells.
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Specimen
4C -/-:
(close )
Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Nr4a2tm1Omc/Nr4a2tm1Omc
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS19: midbrain |
Strong |
Regionally restricted |
4C -/-
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Expression in this mutant is the same as in wild-type.
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Specimen
5A:
postnatal newborn
(more )
Specimen
5A:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS27: midbrain |
Present |
Regionally restricted |
5A
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Expression is ventral in mature dopaminergic neurons.
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Specimen
5B:
(close )
Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Nr4a2tm1Omc/Nr4a2tm1Omc
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS27: midbrain |
Trace |
Single cells |
5B
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Expression is in a few scattered cells in the ventral mid-brain.
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Specimen
5C:
postnatal newborn
(more )
Specimen
5C:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS27: midbrain |
Present |
Regionally restricted |
5C
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Expression is ventral in mature dopaminergic neurons.
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Specimen
5D:
(close )
Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Nr4a2tm1Omc/Nr4a2tm1Omc
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: midbrain |
Trace |
Single cells |
5D
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Expression is in a few scattered cells in the ventral mid-brain.
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