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Gene Expression Data
Assay Details
Assay
Reference: J:308606 Hamada N, et al., Heterotrimeric G-protein, Gi1, is involved in the regulation of proliferation, neuronal migration, and dendrite morphology during cortical development in vivo. J Neurochem. 2021 May;157(4):1167-1181
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6842342
Gene symbol: Gnai1
Gene name: G protein subunit alpha i1
Antibody: anti-Gnai1 (LS-B2546)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2b: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Present Widespread 2b
TS22: cerebral cortex ventricular layer Present 2b An intense signal is enriched at the membrane and its vicinity in some ventricular zone cells in the cytokinetic phase; the signal is not this intense in other mitotic phases.
TS22: cerebral cortex marginal layer Present 2b Expression is seen in mitotic cells.
Specimen 2c - upper: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 2c - upper , 2d - upper An intense signal is enriched at the membrane and its vicinity in some ventricular zone cells in the cytokinetic phase; the signal is not this intense in other mitotic phases.
Specimen 2c - lower: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 2d - lower , 2c - lower An intense signal is enriched at the membrane and its vicinity in some ventricular zone cells in the cytokinetic phase; the signal is not this intense in other mitotic phases.
Specimen 2e/f/g: embryonic day 14.0 (more )
Note: Double labeled: green - Gnai1; red - Pax6 (assay MGI:6842368). Also stained with DAPI (blue).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 2g , 2i , 2h , 2e Some, but not all, of the expressing cells are neural progenitor cells.
Specimen 2j: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex marginal layer Present 2j Expression is seen in mitotic cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory