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Gene Expression Data
Assay Details
Assay
Reference: J:150616 Gutknecht L, et al., Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice. Eur Neuropsychopharmacol. 2009 Apr;19(4):266-82
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6840954
Gene symbol: Tph1
Gene name: tryptophan hydroxylase 1
Antibody: Tph1 antibody
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4Ae: embryonic day 11.25 (more )
Structure Level Pattern Image Note
TS19: brain Absent 4Ae

Specimen 4Be: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: pineal primordium Present Regionally restricted 4Be Expression is in the periphery of the pineal body.

Specimen 5Ba: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: brain Present Regionally restricted 5Ba Expression is in the pineal gland and is absent in the rest of the brain.
TS26: brainstem nucleus Absent 5Ba

Specimen 5Ba inset: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: pineal gland Strong 5Ba inset

Specimen 5Bb: postnatal day 0.5 (more )
Structure Level Pattern Image Note
TS27: brain Present Regionally restricted 5Bb Expression is in the pineal gland and is absent in the rest of the brain.
TS27: raphe nucleus Absent 5Bb

Specimen 5Bb inset: postnatal day 0.5 (more )
Structure Level Pattern Image Note
TS27: pineal gland Strong 5Bb inset

Specimen 5Bc: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted 5Bc Expression is in the pineal gland and is absent in the rest of the brain.
TS28: raphe nucleus Absent 5Bc

Specimen 5Bc inset: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: pineal gland Strong 5Bc inset

Specimen 5Bd: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted 5Bd Expression is in the pineal gland and is absent in the rest of the brain.
TS28: raphe nucleus Absent 5Bd

Specimen 5Bd inset: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: pineal gland Strong 5Bd inset

Specimen 5Be: postnatal day 16 (more )
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted 5Be Expression is in the pineal gland and is absent in the rest of the brain.
TS28: raphe nucleus Absent 5Be

Specimen 5Be inset: postnatal day 16 (more )
Structure Level Pattern Image Note
TS28: pineal gland Strong 5Be inset

Specimen 6Bb: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: pineal gland Present 6Bb
TS28: raphe nucleus Absent 6Bb

Specimen 7Aa: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: pineal gland Strong 7Aa

Specimen 7Ab: postnatal day 0.5 (more )
Structure Level Pattern Image Note
TS27: pineal gland Strong 7Ab

Specimen 7Ac: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: pineal gland Strong 7Ac

Specimen 7Ad: postnatal adult (more )
Structure Level Pattern Image Note
TS28: pineal gland Strong 7Ad

Specimen 8b: postnatal (more )
Structure Level Pattern Image Note
TS28: dorsal raphe nucleus Absent 8b

Specimen 8b inset: postnatal (more )
Structure Level Pattern Image Note
TS28: pineal gland Present 8b inset

Specimen 8d: postnatal; Tph2tm1.2Kpl/Tph2tm1.2Kpl (more )
Structure Level Pattern Image Note
TS28: dorsal raphe nucleus Absent 8d

Specimen 8d inset: postnatal; Tph2tm1.2Kpl/Tph2tm1.2Kpl (more )
Structure Level Pattern Image Note
TS28: pineal gland Present 8d inset

Specimen not shown E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Absent

Specimen not shown E13: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: brain Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory