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Gene Expression Data
Assay Details
Assay
Reference: J:150616 Gutknecht L, et al., Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice. Eur Neuropsychopharmacol. 2009 Apr;19(4):266-82
Assay type: RNA in situ
MGI Accession ID: MGI:6840953
Gene symbol: Tph2
Gene name: tryptophan hydroxylase 2
Probe: Tph2 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4Aa: embryonic day 11.25 (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 4Aa Expression is near the floor plate in the rostro-ventral part of the hindbrain.

Specimen 4Ba: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: brainstem nucleus Present Regionally restricted 4Ba Expression is in serotonergic neurons in raphe nuclei.

Specimen 4Bc: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: pineal primordium Absent 4Bc

Specimen 5Af: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: brainstem nucleus Present Regionally restricted 5Af Expression is in the soma of serotonergic neurons.

Specimen 5Ag: postnatal day 0.5 (more )
Structure Level Pattern Image Note
TS27: raphe nucleus Present 5Ag

Specimen 5Ah: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: raphe nucleus Present 5Ah

Specimen 5Ai: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: raphe nucleus Present 5Ai

Specimen 5Aj: postnatal day 16 (more )
Structure Level Pattern Image Note
TS28: raphe nucleus Present 5Aj

Specimen 6Ac: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: raphe nucleus Strong 6Ac
TS28: pineal gland Absent 6Ac

Specimen not shown E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: central nervous system Absent

Specimen not shown E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: pineal gland Absent

Specimen not shown P0.5: postnatal day 0.5 (more )
Structure Level Pattern Image Note
TS27: pineal gland Absent

Specimen not shown P5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: pineal gland Absent

Specimen not shown P10: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: pineal gland Absent

Specimen not shown P16: postnatal day 16 (more )
Structure Level Pattern Image Note
TS28: pineal gland Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory