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Gene Expression Data
Assay Details
Assay
Reference: J:150616 Gutknecht L, et al., Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice. Eur Neuropsychopharmacol. 2009 Apr;19(4):266-82
Assay type: RNA in situ
MGI Accession ID: MGI:6840952
Gene symbol: Tph1
Gene name: tryptophan hydroxylase 1
Probe: Tph1 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4Ab: embryonic day 11.25 (more )
Structure Level Pattern Image Note
TS19: brain Absent 4Ab

Specimen 4Bb: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: pineal primordium Present Regionally restricted 4Bb Expression is in the periphery of the pineal body.

Specimen 5Aa: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: brain Present Regionally restricted 5Aa Expression is in the pineal gland and is absent in the rest of the brain.
TS26: brainstem nucleus Absent 5Aa

Specimen 5Aa inset: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: pineal gland Strong 5Aa inset

Specimen 5Ab: postnatal day 0.5 (more )
Structure Level Pattern Image Note
TS27: brain Present Regionally restricted 5Ab Expression is in the pineal gland and is absent in the rest of the brain.
TS27: raphe nucleus Absent 5Ab

Specimen 5Ab inset: postnatal day 0.5 (more )
Structure Level Pattern Image Note
TS27: pineal gland Strong 5Ab inset

Specimen 5Ac: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted 5Ac Expression is in the pineal gland and is absent in the rest of the brain.
TS28: raphe nucleus Absent 5Ac

Specimen 5Ac inset: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: pineal gland Strong 5Ac inset

Specimen 5Ad: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted 5Ad Expression is in the pineal gland and is absent in the rest of the brain.
TS28: raphe nucleus Absent 5Ad

Specimen 5Ad inset: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: pineal gland Strong 5Ad inset

Specimen 5Ae: postnatal day 16 (more )
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted 5Ae Expression is in the pineal gland and is absent in the rest of the brain.
TS28: raphe nucleus Absent 5Ae

Specimen 5Ae inset: postnatal day 16 (more )
Structure Level Pattern Image Note
TS28: pineal gland Strong 5Ae inset

Specimen 6Ab: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: pineal gland Present 6Ab
TS28: raphe nucleus Absent 6Ab

Specimen not shown E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Absent

Specimen not shown E13: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: brain Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory