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Med13em1Hko
Endonuclease-mediated Allele Detail
Summary
Symbol: Med13em1Hko
Name: mediator complex subunit 13; endonuclease-mediated mutation 1, Haruhiko Koseki
MGI ID: MGI:6838370
Synonyms: Med13fl
Gene: Med13  Location: Chr11:86157859-86248422 bp, - strand  Genetic Position: Chr11, 51.75 cM
Alliance: Med13em1Hko page
Mutation
origin
Strain of Origin:  Not Applicable
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready, No functional change)
Mutation:    Insertion
    CRISPR-targeting inserted a loxP site downstream of exon 7. (J:316372)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Med13 Mutation:  89 strains or lines available
Notes
The allele was generated at the same time as Med13lem1Hko.
References
Original:  J:316372 Dimitrova E, et al., FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment. Elife. 2018 May 29;7:e37084
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory