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Gene Expression Data
Assay Details
Assay
Reference: J:307035 Chen NY, et al., Increased expression of LAP2beta eliminates nuclear membrane ruptures in nuclear lamin-deficient neurons and fibroblasts. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2107770118
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6832807
Gene symbol: Lmnb2
Gene name: lamin B2
Antibody: anti-Lamin B2
Results
Specimen S3A Lmnb1fl/fl: embryonic day 18.5; Lmnb1tm1.1Sgy/Lmnb1tm1.1Sgy (more )
Note: Double labeled: green - Lmnb2; red - Tmpo (assay MGI:6832801).
Structure Level Pattern Image Note
TS26: cerebral cortex Present S3A Lmnb1fl/fl Lamin b2 , S3A Lmnb1fl/fl merge
Specimen S3A Emx1-Cre;Lmnb1fl/fl: embryonic day 18.5; Emx1tm1(cre)Krj/Emx1+, Lmnb1tm1.1Sgy/Lmnb1tm1.1Sgy (more )
Note: Conditional mutant. Double labeled: green - Lmnb2; red - Tmpo (assay MGI:6832801).
Structure Level Pattern Image Note
TS26: cerebral cortex Present S3A Emx1-Cre;Lmnb1fl/fl Lamin B2 , S3A Emx1-Cre;Lmnb1fl/fl merge In this mutant distribution was disproportionately to one side of the nucleus compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory