Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:230556
Armistead J, et al., Growth arrest in the ribosomopathy, Bowen-Conradi syndrome, is due to dramatically reduced cell proliferation and a defect in mitotic progression. Biochim Biophys Acta. 2015 May;1852(5):1029-37
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:6829676
|
|
Gene symbol:
|
Casp3
|
|
Gene name:
|
caspase 3
|
|
Antibody:
|
anti-cleaved caspase 3
|
|
Detection system:
|
Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
|
|
|
Results
|
Specimen
4E:
(close  )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1
|
|
Mutant Allele(s):
|
Emg1tm1.1Btr/Emg1tm1.1Btr
|
|
Age:
|
embryonic day 8.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS13: embryo |
Present |
|
4E left
,
4E right
|
More generalized staining compared with the controls.
|
Specimen
4F:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1
|
|
Mutant Allele(s):
|
Emg1tm1.1Btr/Emg1+
|
|
Age:
|
embryonic day 8.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
4G:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1
|
|
Mutant Allele(s):
|
Emg1tm1.1Btr/Emg1tm1.1Btr
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS15: embryo |
Present |
|
4G right
,
4G left
|
More generalized staining compared with the controls.
|
Specimen
4H:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1
|
|
Mutant Allele(s):
|
Emg1tm1.1Btr/Emg1+
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Analysis Tools
)
