Tg(Slc10a2-TFRC/OVAL)1Pmall
Transgene Detail
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| Symbol: |
Tg(Slc10a2-TFRC/OVAL)1Pmall |
| Name: |
transgene insertion 1, Paul M Allen |
| MGI ID: |
MGI:6828950 |
| Synonyms: |
OVA-BIL |
| Transgene: |
Tg(Slc10a2-TFRC/OVAL)1Pmall Location: unknown
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| Alliance: |
Tg(Slc10a2-TFRC/OVAL)1Pmall page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Slc10a2-TFRC/OVAL)1Pmall expresses
2 genes
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| chicken |
OVAL (396058) |
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human TFRC fused to OVAL |
| human |
TFRC (7037) |
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human TFRC fused to OVAL |
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Mutation details: The transgenic construct, incorporates the rat Slc10a2 (ASBT) promoter driving expression of the first 118 residues of the human transferrin receptor (TFRC; including the cytoplasmic tail and signal/ancho domain) fused to residues 139-385 of mature chicken ovalbumin cDNA and a polyA tail. The membrane from of ovalbumin is expressed on biliary epithelium.
(J:314919)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:314919 Buxbaum J, et al., Novel model of antigen-specific induction of bile duct injury. Gastroenterology. 2006 Dec;131(6):1899-906 |
| All: |
1 reference(s) |
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