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Gene Expression Data
Assay Details
Assay
Reference: J:226326 Greenlees R, et al., Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization. Hum Mol Genet. 2015 Oct 15;24(20):5789-804
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6828640
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: anti-alpha-SMA
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 6M: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lens anterior epithelium Absent 6M
Specimen 6N: embryonic day 18.5; Sipa1l3Gt(EUCE0020a11)Hmgu/Sipa1l3Gt(EUCE0020a11)Hmgu (more )
Structure Level Pattern Image Note
TS26: lens anterior epithelium Present 6N
Specimen 6O: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: ciliary body Present 6O
TS26: iris Present 6O
TS26: lens anterior epithelium Absent 6O
TS26: lens equatorial epithelium Absent 6O
Specimen 6P: embryonic day 18.5; Sipa1l3Gt(EUCE0020a11)Hmgu/Sipa1l3Gt(EUCE0020a11)Hmgu (more )
Structure Level Pattern Image Note
TS26: ciliary body Present 6P
TS26: iris Present 6P
TS26: lens anterior epithelium Present 6P
TS26: lens equatorial epithelium Present 6P Abnormal cell clusters at the equatorial region were seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory