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Gene Expression Data
Assay Details
Assay
Reference: J:157895 Snippert HJ, et al., Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin. Science. 2010 Mar 12;327(5971):1385-9
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6822347
Gene symbol: Lgr6
Gene name: leucine-rich repeat-containing G protein-coupled receptor 6
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 14.5; Lgr6tm1Cle/Lgr6+ (more )
Structure Level Pattern Image Note
TS22: hair epidermal placode Present 1A
TS22: vibrissa follicle Present 1A

Specimen 1B: embryonic day 14.5; Lgr6tm1Cle/Lgr6+ (more )
Structure Level Pattern Image Note
TS22: hair epidermal placode Present 1B
TS22: epidermis Absent 1B

Specimen 1C: postnatal day 1; Lgr6tm1Cle/Lgr6+ (more )
Structure Level Pattern Image Note
TS27: hair peg Present 1C

Specimen 1D: postnatal day 7; Lgr6tm1Cle/Lgr6+ (more )
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1D Restricted expression is seen above the bulge.
TS28: epidermis Present Regionally restricted 1D Expression is seen in the interfollicular epidermis.

Specimen 1E: postnatal day 20; Lgr6tm1Cle/Lgr6+ (more )
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1E Restricted expression is seen above the bulge.

Specimen 1F: postnatal day 37; Lgr6tm1Cle/Lgr6+ (more )
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1F Restricted expression is seen above the bulge.

Specimen 2B - upper: postnatal; Lgr6tm1Cle/Lgr6+ (more )
Note: Telogen stage.
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present Regionally restricted 2B Lgr6 Expression is seen in the central isthmus.

Specimen 2B - lower: postnatal; Lgr6tm1Cle/Lgr6+ (more )
Note: Telogen stage.
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present Regionally restricted 2B Lgr6 LacZ KI Expression is seen in the central isthmus.

Specimen S1C: embryonic day 15.5; Lgr6tm1Cle/Lgr6+ (more )
Structure Level Pattern Image Note
TS23: hair epidermal placode Present S1C
TS23: vibrissa follicle Present S1C

Specimen S4 - left: postnatal day 56; Lgr6tm1Cle/Lgr6tm1Cle (more )
Note: Second telogen stage. Dividing cells are marked by BrdU.
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present S4_left Expressing cells are not marked by BrdU.
TS28: hair follicle bulge Absent S4_left

Specimen S4 - right: postnatal day 56; Lgr6tm1Cle/Lgr6tm1Cle (more )
Note: Second telogen stage. Dividing cells are marked by BrdU.
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present S4_right Expressing cells are not marked by BrdU.
TS28: hair follicle bulge Absent S4_right

Specimen S9 - E14.5: embryonic day 14.5; Lgr6tm1Cle/Lgr6+ (more )
Structure Level Pattern Image Note
TS22: vibrissa follicle Present S9_E14.5

Specimen S9 - E15.5: embryonic day 15.5; Lgr6tm1Cle/Lgr6+ (more )
Structure Level Pattern Image Note
TS23: vibrissa follicle Present S9_E15.5

Specimen S9 - Adult (upper): postnatal adult; Lgr6tm1Cle/Lgr6+ (more )
Note: Snout area.
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present Regionally restricted S9_Adult upper Expression is seen in the centra isthmus.

Specimen S9 - Adult (lower): postnatal adult; Lgr6tm1Cle/Lgr6+ (more )
Note: Snout area.
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present Regionally restricted S9_Adult lower Expression is seen in the centra isthmus.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory