Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Setd4em1(cre)Wjy
Name:	SET domain containing 4; endonuclease-mediated mutation 1, Wei-Jun Yang
MGI ID:	MGI:6822324
Synonyms:	SETD4-Cre
Gene:	Setd4  Location: Chr16:93380345-93400951 bp, - strand  Genetic Position: Chr16, 54.52 cM
Alliance:	Setd4em1(cre)Wjy page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Setd4em1(cre)Wjy expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Setd4 (MGI:2136890)   Mutation details: Using CRISPR/Cas9 technology, a T2A-Cre-WPRE-PA cassette was inserted into the 3'-end SETD4 coding region. (J:314227)

Activity:	Tissue activity of this recombinase allele
Driver:	Setd4 (mouse) Summary of all recombinase alleles driven by Setd4. Comparative matrix view of recombinase activities Alliance mouse Setd4 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Setd4 Mutation:	28 strains or lines available

Original:	J:314227 Tian JZ, et al., SETD4-expressing cells contribute to pancreatic development and response to cerulein induced pancreatitis injury. Sci Rep. 2021 Jun 15;11(1):12614
All:	4 reference(s)